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Video Transcript: How to Kill Cancer Stem Cells
Ty Bollinger: Okay. You mentioned stem cells.
Dr. Bradford Weeks: Right. For the past seven years – I am one of four doctors now that is qualified to teach insulin potentiated chemotherapy; IPT. And that is a fabulous way to do chemotherapy. So fabulous that I just think it is illogical for anyone who is going to get chemotherapy… if they want to do chemo they should do IPT.
A couple of quick reasons and this might be included in other people discussing it. You have to know that when you give insulin it shifts the cancer cells to what is called the S phase or the synthesis phase or the active phase. And that’s the only phase that chemotherapy can be effective.
So you have really four phases that the cancer cell can be in. So you’ve got a 25% chance if you give chemo that it’s going to kill the cancer cell. If you give insulin beforehand it pushes it to about 70% S phase. So now you’ve got almost a three out of four chance to kill cancer cells. If you are going to give chemo, let’s kill the cancer cells. Just giving a little insulin pushes the cells into the vulnerable phase.
The second thing I like about insulin potentiated chemotherapy is that when you give the insulin it makes the cell membranes not only more permeable to chemotherapy selectively, compared to your other healthy cells, but it also inhibits the cancer cell from kicking out the toxic chemotherapy.
So, as good as IPT is I don’t offer it anymore. The reason I don’t is it only kills tumors. Cancer tumors are not the real target. Cancer stem cells, which is usually about less than 3% of the tumor mass would be the cancer stem cell. These are the ring leaders. These are the guys that are fermenting a riot and they have their lieutenants. For the most part a group riot is really composed of bystanders who watch and maybe go along. The tumor is not dangerous. The primary tumor rarely kills people. Unless it grows big enough to obstruct an airway or an artery or something. But it is the metastatic process that is dangerous.
What we now know from people like Professor Max Wicha; Max Dean at Stanford. [Dr.] Wicha is in Michigan. The literature, if you search “cancer stem cells” and Google it; if any of the patients will search “cancer stem cells” they will see that the cancer stem cell is the real target. And one of my favorite quotes is Thomas Pynchon in “Gravity’s Rainbow.” He says if you can get people to ask the wrong question, the answer doesn’t matter.
The wrong question being asked is “how can we shrink tumors, how can we kill tumors?” All my good, wonderful colleagues are targeting the tumors. For the last six years I have been the only one saying “you’ve got to go after the cancer stem cells.”
If you shrink the tumor it’s not correlated to longevity. If you attack the tumor effectively it will, as injured tissue, secrete an inflammatory cytokine to recruit uncommitted stem cells from the mezankine[ph] to migrate to the injured tissue, the cancer, which was attacked by the chemo.
Now here come these stem cells to the attacked tumor, injured tissue. And they say “here we come.” By the way, what would you like us to become? And they become a tumor. That is why Max Wicha is on record, a distinguished professor of oncology. Max Wicha is on record for saying chemotherapy and radiation make your cancer worse.
But you can’t just stop a gazillion dollar industry in its tracks and have everyone say to their patients, “Sorry, no chemo today.” Our gurus have told us not. Until they can start making money on an anti-inflammatory, which is what they are working on now. Because the anti-inflammatory will stop the recruitment of the stem cells which become cancer stem cells.
Anyway, the thing I wanted to say there is that the real target is to stop cancer stem cells for three reasons – only they metastasize. Tumor cells don’t metastasize. The cancer stem cell metastasizes. The cancer stem cells are resistant to chemo and radiation. So you can do what you want with chemo and radiation. You are not targeting the real villain, the real culprit.
The third thing is that if you don’t address the cancer stem cells your cancer is coming back because those are the ones that can recreate a cancer. But nobody is targeting them. So I say to my clients if you are going to see your oncologist ask him or her, “What are you going to do to help me be healthy while you kill my tumor?” Because that is all they can do. Current oncologists are only killing tumors and patients, but they are not killing cancer stem cells.
The second question is, “What is your treatment going to do to my cancer stem cells?” And Ty, then they have to watch the eyes of the oncologist. Because if they get kind of a blank stare like what are you talking about then they are not up to speed on literature and you have to run away. And if they give this oh damn, I’m busted kind of sideways look, then it is a really unfortunate situation because they know that their treatments aren’t helping. They are just using the patient as a renewable resource, which is tragic. So cancer stem cells need to be addressed and currently the only way to do that is anti-inflammatories.
Ty Bollinger: And the anti inflammatories help to kill the cancer stem cells?
Dr. Bradford Weeks: There is literature that says, for example, metformin selectively targets cancer stem cells. There are a lot of agents out there that selectively target cancer stem cells.
Ty Bollinger: And metformin, is that a drug?
Dr. Bradford Weeks: It is a blood sugar lowering drug. But there are arthritis drugs – aspirin. Too much aspirin will kill you, but you got to have some anti-inflammatories. We use a product called Soul which is ground up black cumin seed, black raspberry seed, and chardonnay grape seed. These are very powerful anti-inflammatory seeds, which have been well studied. Water. Tremendous benefit just by having good quality water to flush your system. Seeds have oil in them and oils help restore a membrane of cells integrity. A lot of benefits to eating the seeds.
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