Enzymes play a vital role in human health and well-being. They are imperative for optimal digestion, nutrient absorption, immune response, cognitive thinking, and systemic cellular detoxification, among many other life-essential processes. Since the early 1900s enzyme therapy has been used as a natural protocol to heal cancer and has showed tremendous promise.
Enzymes are protein structures which take on different shapes and are designated for different purposes, such as one might compare a lock and key model. Enzymes are some of the most important structures in your body. They help heal and support good immune response to help prevent disease and cancer.
Enzymes have catalytic responsibilities. This means they help speed up the rate of chemical reactions in the body and better enable biological processes to occur. It is estimated that we have over 7,000 reactions in our bodies which take place with the assistance of 3,000 specific enzymes.
Your digestive tract relies on many different types of proteolytic enzymes to help break down your food. Proteolytic enzymes are a type of digestive enzyme that break down protein into amino acids. When taken on an empty stomach, proteolytic enzymes pass into the bloodstream and become Systemic enzymes. Systemic enzymes are enzymes that work outside of the digestive system and participate in the reactions within your body’s cells.
The Role of Systemic Proteolytic Enzymes on Cancer
A thick outer coating called fibrin covers cancer cells. This coating is used to shield cancer cells from the immune system. Not only does the fibrin keep the immune system from identifying and destroying the cancer cells, it prevents chemotherapy from doing the same thing unless the chemo is used at industrial strength doses.
The use of systemic proteolytic enzymes allows lower doses of chemotherapy to be utilized. It also helps to reduce the side effects of chemotherapy and to limit the waste buildup produced during treatment.
Some of the side effects of chemotherapy include vomiting, diarrhea, fatigue, pain and nausea. Enzyme therapy has shown promising results in limiting these symptoms by reducing the cytotoxic (poisonous) effects that chemotherapy has on the body.
Radiation Therapy, Surgery, and Enzymes
Radiation therapy for cancer causes organ damage and rigid scar tissue in the affected organ. This scarring limits the function of the organ. Proteolytic enzymes, however, can prevent the buildup of scarring and stimulates organ function by diminishing pre-existing fibrosis (formation of excess tissue). Proteolytic enzymes also assist individuals undergoing surgical procedures by speeding up recovering time.
Systemic Proteolytic Enzymes and the Immune System
Research shows that enzyme therapy decreases inflammation, stimulates cytokine production, and increases the defensive powers of natural killer cells and macrophages. Both natural killer cells and macrophages scan the body seeking abnormal cancer cells and viruses. Stimulating these immune system defenses reduces the risk of cancer developing, growing and spreading.
Systemic enzymes regulate the activity of the numerous responses of the immune system. They are attracted towards pro-inflammatory cytokines including tumor necrosis factor (TNF) and C- reactive protein(CRP). Enzyme therapy can be used to decrease the over stimulated activity of tumor growth factor-beta at the site of protein synthesis. There have been no major adverse side effects from the use of systemic enzyme supplementation.
Enzymes Have Anti-Proteinase Activity
Anti-proteinases, including α-1-antitrypsin and α-2-macroglobulin, are found to bind irreversibly to systemic enzymes. When this occurrence happens, other anti-proteinases are stimulated and shut off the function of tumor regulating proteinases such as cathepsin. As a result, cancer metastasis is inhibited.
In fact, the field of oncology is increasingly using the ratio of proteinases to anti-proteinases to make a cancer prognosis. Papain and bromelain are cysteine groups found in proteinase components and can influence tumor development.
Adhesion factors which play a critical role in tumor growth and metastasis are CD-44, CD-49, CD-54, and CD-58. Enzymes interact with these adhesion factors. They also promote antioxidant enzymes which in turn reduces free radicals. Reactive oxygen species is a potent free radical which causes havoc on the body and also by initiating oncogene expression.
Systemic Enzyme Use
Systemic enzyme supplementation is best coming from an array of plant and animal enzymes. When you consume raw, sprouted, and fermented vegetables and fruits you are taking in more enzymes. Three of the best plant-based proteolytic enzymes include papain, bromelain and rutin. Chymotrypsin, pancreatin, and trypsin are enzymes from animals.
Systemic enzymes are formulated to reach the bloodstream fully intact and not become dissolved in stomach acid. To ensure optimal absorption, systemic proteolytic enzymes should be consumed on an empty stomach. This allows for their passage into the bloodstream where they can then be circulated throughout the entire body. Specific protease enzymes which break down protein have been found to have a powerful impact on fighting inflammatory and fibrinolytic activity (blood clot formation).
High Dose Enzyme Therapy and Intermittent Fasting
When systemic enzymes are used in conjunction with intermittent fasting, a synergy of benefits exists. Practicing intermittent fasting for periods of 16 to 18 hours can improve immune system support, increase human growth hormone, and better equip the body with a better source of fuel for the brain and body in the form of ketones. Intermittent fasting has also been shown to improve hormone signaling as well as to stabilize blood sugar, and increase fatty acid metabolism.
High dose enzyme therapy is best recommended for individuals who use intermittent fasting to heal. In order to be most effective, systemic enzyme therapy must take place outside a period of food consumption.
The best time for enzyme supplementation is during the morning when most people can fast on cleansing herbal beverages and lemon water. Furthermore, it is also recommended to go to sleep on a stomach that is not trying to digest and absorb nutrients from a meal too recently consumed before bedtime. If you are not a morning faster, high dose enzyme therapy may be more appropriate for you before bedtime.
Dosing Recommendations for Enzyme Therapy
Cancer Prevention: 5 to 20 grams daily. Preferably 10 capsules in the morning and 10 capsules before bed.
Cancer Patients: 20 to 80 grams proteolytic enzymes daily. Dosage split into 30 capsules in the morning, 20 capsules 3 hours later (preferably 2 hours before and after eating), and 30 capsules before bed.
Metastatic Cancer Patients: 45 to 160 grams daily split into 40 capsules in the morning, 40 capsules later, and 80 capsules before bed.
Article Summary
Since the early 1900s enzyme therapy has been used as a natural protocol to heal cancer. Enzymes are essential for optimal digestion, nutrient absorption, stimulating immune response, cognitive thinking, cellular detoxification, and other processes.
Proteolytic enzymes are a type of digestive enzyme that break down protein into amino acids. Systemic enzymes are enzymes that work outside of the digestive system and participate in the reactions within your body’s cells. When proteolytic enzymes are consumed on an empty stomach, they pass through into the blood and become systemic enzymes.
The use of systemic enzymes allows lower doses of chemotherapy to be used. It also helps to reduce the side effects of chemotherapy and to limit the waste buildup produced during treatment. System proteolytic enzymes assist people undergoing surgical procedures by speeding up recovering time and reducing scar tissue.
Enzyme supplementation is best coming from an array of plant and animal sources. Three of the best plant-based proteolytic enzymes include: papain (from papaya), bromelain (from pineapple), and rutin (from asparagus & buckwheat).
Systemic enzymes are formulated to reach the bloodstream fully intact and not become dissolved in stomach acid. There is a synergistic effect when using systemic enzymes in conjunction with intermittent fasting.
Dosing Recommendations for Enzyme Therapy:
- Cancer Prevention: 5 to 20 grams daily. Preferably 10 capsules in the morning and 10 capsules before bed.
- Cancer Patients: 20 to 80 grams proteolytic enzymes daily. Dosage split into 30 capsules in the morning, 20 capsules 3 hours later (preferably 2 hours before and after eating), and 30 capsules before bed.
- Metastatic Cancer Patients: 45 to 160 grams daily split into 40 capsules in the morning, 40 capsules later, and 80 capsules before bed.











Thanks for these infos I was going to ask you where can we find thoses enzymes .,so I have heard that spargus also Could give you kidney stones…just a saying that I heard years ago I don’t know if it is’true..they at that time talked about acid uric..so if you know anything about that would appreciate..and beside those three fruits and vege would you know of others vege and fruits that would contain also those enzymes?..cause people not living in southern reas for pinepples ..and other would appreciate very much to know…..do you think that canned pineapple would be as good as the fresh ones?..I doubt because of the heat they go throu to be put in a can thou…thank you very very much…
Ok Great article but where is the link to the supplement you’re talking about?
There are several great systemic enzyme products on the market. The one I use is Wobenzyme here: http://store.drjockers.com/products/wobenzym
Capucine, I would DEFINITELY not recommend canned pineapple. I would recommend finding a proteolytic enzyme supplement and taking the standard dosage each day to get these benefits.
Yes thanks doc about your advice in reality I just asked this question.if one day we were out of everything as a world wide catastrophy let say…
Well just pointed out that I just finished hearing Charlotte Gerson …I will give you the link here…https://www.youtube.com/watch?v=aYYlX8aRj3E
Even thou I know almost everything she said makes me happy to hear it again and…little details which aren’t really…like drinking very very fresh juices ..not juices even from the morning kept in fridg…right on the spot…enzymes dies after a short time…
…and other things..
She spoke about genetics also..saying that yes it can stop cancer ..but doesn’t stay stopped fter. While it comes back…..certainly ..it is my guess…that we don’t keep up eting to keep the alcalinity of the body way up.. …
This video is very interesting she is 91yers old..and if you can once you see it..tkes an hour..yes a little long but worth it….so if you jve time tell me what you think ..i believe as what she said several times….that all is mingled…all is interconnected….and of course who can deny this..also we hve to know what to do to begin by detoxifying…to do it wisely…how to begin intelligently,,to keep going..silently but surely..while we can..nd get things in our body better little by little..thanks for reading…
I am too old now but really all this is sooo interesting..it is a link to spirituality ..when the body is in shape..we can go a long long way in all directions…….
My mum is taking 3000 gdu per day bromelian for her metastatic cancer, how does that compare to the dosage you suggests for cancer? How many gdu per day is it safe for her to take?
Hi I use wobenzyme as well but at the dose on the bottle, how long do you recommend using the cancer treatment and metastatic dose for? A day? A week? For ever? The wobenzym is pretty expensive do you know of a liquid form?
Are you serious? 80 capsules a day (systematic enzymes) for metastic cancer?
That means nearly an entire bottle every day & at $30 a bottle, most of us can’t afford that!
I take over 50 different capsules a day now & find it very challenging at that!
masszymes by Bioptimizers is the brand I use.
Most proteins breakdown in the stomach through proteolytic action of stomach enzymes. Can you give a reference of research showing evidence that bromelain and papain are absorbed into the blood stream if consumed on an empty stomach?
thank you for this important information……I need this infor. but didnt get it from any of my cancer doctors nor the nutritionist……I hope to read more about these ideas to prevent cancer……renee ^.^
How would you use the fruits, rather than the tablets?
Can you purchase in Canada?
Yes I am sure you can get these in health food stores in Canada. Wobenzyme is a popular product
sounds good but I would rather take the fruits than pills…..foods have everything we need…its just that many of us dont know how to choose whats better for us…….I am learning all the time ……^.^
Yes everyone, it is expensive and not at all convenient because you have to take A LOT of pills outside of meals (at least an hour and preferably 2+ hours) to get the astonishing results described in the article. This is a therapy that Nickolas Gonzalez has used and has hundreds of documented cancer healing testimonials. His top 3 therapies were strict diets, very high dose enzyme therapy and coffee enemas. Not the most fun but this saved lives and still does today!
As a clinician, I have had trouble getting people to be compliant due to the cost and amount of pills people need to swallow. Most people think that natural methods only involve a diet and lifestyle change, and that is the foundation, but just like the conventional method, which uses expensive and uncomfortable treatments such as chemo and radiation….natural strategies can often be expensive and uncomfortable (although significantly less cost than conventional and not nearly as uncomfortable).
Ultimately, you choose the route you want to take. Eating the fruits may be good, but you won’t get the amount of enzymes you need to get the kind of results described in the article. Hope that helps clear up some confusion. I take 10 caps – 2x daily myself and LOVE IT! Less pain, better skin, better exercise recovery, improved immunity and energy are the side effects!
You take 10 caps – 2x daily of Wobenzyme? The reason I don’t take Wobenzyme is because they come in tablets, not capsules. Any other enzyme product you would recommend, preferably in a capsule form?
is Inf-zyme the same basic product as Wobenzyme?